Instruments for miRNA in situ Hybridization (ISH):

BioGenex is a pioneer in the design, development and manufacturing of advanced systems for automation of cell and tissue-based staining. The Xmatrx research systems (NANO, MINI and Infinity) are the direct result of our platform technology innovation. They offer a variety of automation, throughput and assay applications for translational and clinical research. Our key technology differentiators, including the eXACT temperature control and reaction micro-chamber, enable any slide-based assays such as immunohistochemistry (IHC), in situ hybridization (ISH), fluorescence in situ hybridization (FISH), immuno-fluorescence (IF), co-detection and multiplex applications (double and triple stains; IHC/ISH), in situ PCR, micro-RNA and special staining.


Features & Benefits:

  • All-in-One – FISH, in situ PCR and ISH
  • Add micro-reagents manually to save cost
  • Economical and affordable
  • Flexible open system software – to create, edit and save protocols for future use
  • Run 10 different protocols simultaneously

Features & Benefits:

  • High throughput – 100 slides per day (60 slides in eight hour shift and 40 slide in a overnight run) with overnight run option
  • Multiple slide processing options – Random, Continuous and STAT
  • Liquid level sensor for accurate dispensing and real time reagent tracking – avoid false results
  • Disposable tips – no cross-contamination
  • Onboard final coverslipping (proprietary)
  • Auto-DAB enabled
  • LIS interface
  • 2D Barcode-enabled scanning technology
  • Partial auto-drain waste disposal system
  • Removable Slide Racks with Splash Guard
  • Reaction micro-chamber with optimal microfluidics
  • 40 independent temperature control and protocols
  • Wide reagent volume dispense range(10µL-800µL)

Features & Benefits:

  • Intelligent and flexible system offering infinite possibilities – IHC, IF ISH, FISH, CISH, IF, Multiplexing and in situ PCR.
  • Simultaneous optimization of up to 40 parameters in single run
  • Reaction micro-chamber reduces micro-reagent consumption by up to 90%
  • 40 independent thermocyclable (PCR) workstations
  • Intuitive software designed for ease of use and flexibility
  • Reports for inventory management and regulatory compliance
  • Multiple slide processing options – Random, Continuous and STAT

Features & Benefits:

  • in situ PCR and FISH Work Station
  • Hybridizer with eXACT™ temperatures
  • 10 independent thermal cyclers
  • Built-in touch screen display for easy operations
  • On-board wash with effective waste drainage system
  • Audio-visual alerts at every step for manual intervention
  • User-friendly software with ability to add or delete cycles, store protocols for future use and perform up to 45 PCR cycles

Features & Benefits:

  • Add micro-reagents manually to save cost
  • Automated oil sealing and coverslipping to avoid reagent evaporation
  • eXACT temperature control on every slide
  • Open system software – create, edit and save protocols for future use
  • Run 10 different protocols simultaneously
SpecificationsNanoVIP®Xmatrx® ELITEXmatrx® InfinityXmatrx® MINIXmatrx® NANO
AutomationFull AutomationFull (baking through coverslip)Full (baking through cover slip)Work StationWashing, coverslipping, slide drying
Run Time (full slide load)Open System / User definedClosed System / User definedOpen System / User definedOpen System / User definedOpen System / User defined
Temperature RangeAmbient to 105 oCAmbient to 105 oCAmbient to 105 oCAmbient to 105 oCAmbient to 105 oC
Reagent Dispensing Volume10-180 µl10-800 µl10-800 µlNANA
Slide Capacity1040401010
Reagent Capacity244949NANA
Bulk Reagent Carboy5 x 1 L7 x 4 L7 x 4 LNA6 x 1 L
Waste Container4 L8 L8 L2 L4 L
Languages enabledEnglishEnglishEnglishEnglishEnglish
LIMS option
ProtocolsTemplate / Self user definedPreloaded >400 protocolsTemplate / SelfTemplate / SelfTemplate / Self
Dimensions (D/W/H)20”/30”/20”29” x 66” x 59”29”/46”/59”19.5”/13”/8”20″ x 30″ x 15.7″
Weight106 lb/ 48 kg400 lb/182 Kg400 lb/ 182 kg30 lb/ 13.6 kg94 lb/43 Kg


Research Platforms /ApplicationIHCISH/CISHDouble StainingFISHIFmiRNA ISH



In Situ PCR
Xmatrx® Infinity
Xmatrx® MININA