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Nucleophosmin
SKU: AMD46GP Categories: , ,

Nucleophosmin (NPM1or nucleolar phosphoprotein B23 or numatrin) is a highly phosphorylated nucleolar protein involved in the assembly of ribosomal proteins into ribosome in nucleolus and maintenance of genome stability. A high level of nucleophosmin stimulates the growth of normal cells and is abundantly expressed in tumour cells than in normal resting cells. Mutations involving nucleophosmin were found in acute promyelocytic leukemia, acute myelogenous leukemia, nonHodgkin lymphoma and myelodysplastic syndrome.

Intended Use

IVD

Antibody Type

Nucleus and Cytoplasm

Clone

rNPM1/1901

Source

Mouse

Tissue Type/Cancer Type

Colon , Skin tissues

Pack

1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 6 mL – Manual – RTU, 10 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 160 Tests – Automation – Xmatrx