Gastrin is a linear peptide hormone that regulates the secretion of gastric acid by gastric mucosa in the stomach. It is produced by G-cells of the pyloric antrum, D cells of the pancreatic islets and duodenal mucosa. Gastrin is regulated by epidermal growth factor and also enhances the smooth muscle contraction, secretion of hydrochloric acid (Hcl), increases blood irculation and water secretion in the stomach and intestine. It is expressed in G-cells of antral/pyloric mucosa, cells producing gastrin and is useful in differentiating gastric-secreting neoplastic and nonneoplastic neuroendocrine cells.
Intended Use: IVD
Antibody Type: Extracellular/secreted
Clone: GAST/2634
Source: Mouse
Tissue Type/Cancer Type: Pituitary, Stomach tissues

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