Cytokeratin 5 is a 58kDa type II (basic) intermediate filament protein belongs to the cytokeratin family. It plays a crucial role in organization of cell adhesion, tissue specialization and function to maintain structural integrity of the integument. CK5 expression is seen in keratinized and non-keratinized stratified squamous epithelia, myoepithelial cells in normal mammary glands, glandular epithelia and normal basal cells in prostate glands. Anti-Cytokeratin 5 is a useful marker in differential diagnosis of Epithelial Mesotheliomas from metastatic pulmonary adenocarcinomas.
|Tissue Type/Cancer Type||
Tonsil. Esopahgus, bladder, prostate, Skin BCC tissues
1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 6 mL – Manual – RTU, 10 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 160 Tests – Automation – Xmatrx