DatasheetSDS

The Beta Actin probe detects Beta Actin-encoded RNA in formalin-fixed, paraffin-embedded human tissues by in situ hybridization. Beta Actin-encoded RNA, remains a widely used housekeeping gene internal control for human FFPE tissues. However ACTB is closely associated with a variety of cancers and accumulating evidence indicates that ACTB is deregulated in liver, melanoma, renal, colorectal, gastric, pancreatic, esophageal, lung, breast, prostate, ovarian cancers, leukemia and lymphoma. The detection of Beta Actin mRNA with BioGenex automated in situ hybridization technique will provide evidence of intact mRNA in tissues.