YAP encodes a nuclear effector of the Hippo signaling pathway which plays a pivotal role in regulating tissue growth and organ size. Deregulation of the Hippo pathway causes tumor formation and malignancy and hence, YAP may function as a potential target for cancer treatment. YAP is expressed at high levels in the lung, placenta, prostate, testis and ovary.
|Tissue Type/Cancer Type||
Breast Carcinoma Tissue
6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual