YAP encodes a nuclear effector of the Hippo signaling pathway which plays a pivotal role in regulating tissue growth and organ size. Deregulation of the Hippo pathway causes tumor formation and malignancy and hence, YAP may function as a potential target for cancer treatment. YAP is expressed at high levels in the lung, placenta, prostate, testis and ovary.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: G-6
Source: Mouse
Tissue Type/Cancer Type: Breast Carcinoma Tissue

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