DatasheetSDS

Vimentin, is a key component of the protein intermediate filament family, is more commonly expressed in mesenchymal cells and helps to maintain cell integrity and protect cells against mechanical stress. Vimentin has been observed to be over expressed in certain cancers like epithelial cancers, tumors of the central nervous system, including prostate cancer, gastrointestinal tumors, breast cancer, malignant melanoma, and lung cancer, nevertheless, the expression of vimentin in cancer progression remains to studied in detail and how the Vimentin’s over expression in cancer correlates well with accelerated tumor growth, invasion, and poor prognosis; In recent years, vimentin has been recognized as a potential marker for epithelial-mesenchymal transition (EMT), however the role of vimentin’s remains unknown. More research has to be done to evaluate its specific role in cancer