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Anti-Tyrosinase

SKU: AM535GP Categories: , ,
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Product Description

Tyrosinase catalyses phenol oxidation and is generally present in plants and animals. Tyrosinase is a metallo enzyme containing copper, tyrosinase present in tissues catalyze oxidation of tyrosine and produces melanin and other pigments. The Microphthalmia- associated transcription factor gene regulates Tyrosinase. A tyrosinase gene mutation leads to mutated tyrosinase production uncapable of tyrosine oxidation that results in type I oculocutaneous albinism, a hereditary disease that one in every 17,000 person has in the US. Anti-Tyrosinase has been found to be quite specific for melanotic lesions such as malignant melanoma, and melanotic neurofibroma. Essentially no carcinomas express this marker

Intended Use

IVD

Antibody Type

Monoclonal

Clone

Ty/G5

Source

Mouse

Tissue Type/Cancer Type

Melanoma

Pack Size

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual