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Anti-TTF-1, Clone NX2.1/690

SKU: AMA25GP Categories: , , ,
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Product Description

Thyroid Transcription Factor-1 (TTF-1), also known as thyroidspecific enhancer-binding protein (T/EBP), is a 40 kD protein that is a member of NKx2 family of homeodomain transcription factors that regulates the expression of thyroid- and lung-specific genes. It is a very selective marker for adenocarcinomas of lung and thyroid origin. Nuclear localization of this protein is seen in the epithelial cells of thyroid gland and lung. The anti-TTF-1 antibody is a useful tool for differentiating pulmonary adenocarcinoma from metastatic breast carcinoma and mesothelioma.

Intended Use

IVD

Antibody Type

Monoclonal

Clone

NX2.1/690

Source

Mouse

Tissue Type/Cancer Type

Lung cancer

Pack

6 mL (RTU), 10 mL (RTU), 1 mL(Conc.), 0.5 mL (Conc.), 200 tests – Xmatrx Elite, 50 tests – Xmatrx Elite, 5 slides – Xmatrx, 5 slides – Manual