Thyrotrophs produce thyroid stimulating hormone (TSH). TSH is a 28 kD glycoprotein that contains 201 amino acid residues and is composed of alpha and beta subunits. The alpha subunit (MW 13kD) is immunologically similar to the alpha subunit of the other anterior pituitary hormones. The beta sub-unit is unique to TSH and is responsible for the specific biological activity of TSH. To identify thyrotrophs without crossreactivity with gonadotrophs, antibodies directed to the TSH beta subunit must be used.
Intended Use | IVD |
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Antibody Type | Monoclonal |
Clone | 5404 |
Source | Mouse |
Tissue Type/Cancer Type | Pituitary |
Pack | 6 mL – Manual – RTU, 100 Tests – Automation – i6000, 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP®, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |