Anti-Thymidylate Synthase


Thymidylate Synthase (TS or TYMS) is a 36kDa intracellular enzyme catalyzes deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP) which is essential for DNA biosynthesis or DNA repair. It is also an important target for fluoropyrimidines, an important group of antineoplastic drugs (e.g: 5-fluorouracil (5-FU)) which acts TS inhibitor and are widely used in the treatment of solid tumors such as breast, colon, head and neck.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: TYMS/1884
Source: Mouse
Tissue Type: Prostate carcinoma Tissue