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Anti-SV40 T Ag [Pab 101]

SKU: AMB74-5M_GP Categories: , , ,
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Product Description

Simian virus (SV40) T (large and small) antigens are encoded by the early region of the SV40 genome. The large T antigen of SV40 binds DNA, and complexes with a 53KDa cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition, it also binds DNA polymerase and the transcription factor AP-2 to form a specific complex with the P105 product of the retinoblastoma susceptibility gene. SV40 also forms complexes with a second tumor supressor gene-encoded protein, Rb 105.

Intended Use

IVD

Pack

6 mL (RTU), 10 mL (RTU), 1 mL(Conc.), 0.5 mL (Conc.), 200 tests – Xmatrx Elite, 50 tests – Xmatrx Elite, 5 slides – Xmatrx, 5 slides – Manual