Anti-SV40 T Ag [Pab 101]
![Anti-SV40 T Ag [Pab 101]](https://biogenex.com/wp-content/uploads/2021/10/SV40_AMB74_40X_3.jpg)
Simian virus (SV40) T (large and small) antigens are encoded by the early region of the SV40 genome. The large T antigen of SV40 binds DNA, and complexes with a 53KDa cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition, it also binds DNA polymerase and the transcription factor AP-2 to form a specific complex with the P105 product of the retinoblastoma susceptibility gene. SV40 also forms complexes with a second tumor supressor gene-encoded protein, Rb 105.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Source | Mouse |
| Clone | Pab 101 |
| Tissue Type | Colon tissue |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual, 50 tests – NanoVIP® |
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