Menu

Anti-Substance P

SKU: AR069GP Categories: , , ,
Clear

Product Description

Substance P (SP) is a neuroendocrine polypeptide localized in both the nervous system and gastrointestinal tract and it is secreted by nerves and inflammatory cells such as macrophages, eosinophils, lymphocytes, and dendritic cells, it acts by binding to the neurokinin-1 receptor (NK-1R). Substance P along with bombesin and neurotensin grouped into a family since they?re localized in both brain and gut and posses a common dipeptide sequence (-Leu-Met-NH 2 ) at the amino terminal end. Substance P is found localized in mid-gut and about half of fore-gut and hind-gut intestinal carcinoids. This antibody cross-reacts with other species Substance P including chicken and opossum.

Intended Use

IVD

Antibody Type

Polyclonal

Clone

Polyclonal

Source

Rabbit

Tissue Type/Cancer Type

Hypothalamus

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual