DatasheetSDS

Spectrin is an actin binding protein and a major constituent of cytoskeletal superstructure of the erythrocyte plasma membrane. Erythrocyte Spectrin is a heterodimer made up of alpha-beta dimers linked in a head-to-head arrangement. Spectrin in other tissues may be composed of distinct but homologous alpha and beta subunits, sometimes referred to as Fodrin. It functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It also functions as membrane organizers and stabilizers, composed of non-homologous are present in other somatic cells.