The SOX10 protein belongs to the SOX genes family of transcription factors that bind to the minor groove in DNA. They are characterized by a homologous sequence called the HMG-box. SOX10 is known to be involved in regulation of embryonic development and determination of cell fate. It combines with other proteins to form complexes and acts as a transcriptional activator. It is very important for neural crest and peripheral nervous system development. SOX10 plays an important role in melanocytic cell differentiation. It can be used as a sensitive marker for melanoma.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | SOX10/991 |
| Source | Mouse |
| Tissue Type/Cancer Type | Salivary Gland |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
