The SOX10 protein belongs to the SOX genes family of transcription factors that bind to the minor groove in DNA. They are characterized by a homologous sequence called the HMG-box. SOX10 is known to be involved in regulation of embryonic development and determination of cell fate. It combines with other proteins to form complexes and acts as a transcriptional activator. It is very important for neural crest and peripheral nervous system development. SOX10 plays an important role in melanocytic cell differentiation. It can be used as a sensitive marker for melanoma.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: SOX10/991
Source: Mouse
Tissue Type/Cancer Type: Salivary Gland