Sox-11 is a neural transcription factor that belongs to group C SOX (SRY-related HMG-box) transcription factor family. It is involved in the embryonic neurogenesis and plays a role in epithelial-mesenchymal interactions, tissue modelling during development, neuronal cell proliferation, and survival. SOX-11 is also involved in tumorogenesis and adult neurogenesis. Its expression is prominent in the periventricular cells of the developing central nervous system, Mantle cell lymphoma, and in subsets of hairy cell leukaemia, B cell lymphoblastic leukaemia, Burkitt lymphomas, but is not expressed in other B cell lymphomas or in normal B lymphocytes. Sox11 is also expressed in malignant gliomas and epithelial ovarian cancer.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | SOX11/7236 |
| Source | Mouse |
| Tissue Type/Cancer Type | Mantle cell Lymphoma, Tonsil, Lymph node tissues |
| Pack | 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
