Anti-Serum Amyloid P, Clone APCS/3240
Serum Amyloid P (SAP), a member of pentraxin family, is a glycoprotein which has a characteristic pentameric organization. It is an acute phase protein, structurally related to C-reactive protein. SAP is made by hepatocytes and secreted into the blood. SAP is the single normal circulating protein that shows specific calcium-dependent binding to DNA and chromatin in physiological conditions. The avid binding of SAP displaces H1-type histones and thereby solubilizes native long chromatin, which is otherwise profoundly insoluble at the physiological ionic strength of extracellular fluids. The normal plasma protein serum amyloid P component (SAP) binds to fibrils in all types of amyloid deposits, and contributes to the pathogenesis of amyloidoses.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Source | Mouse |
| Clone | APCS/3240 |
| Tissue Type | Liver tissue |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual, 50 tests – NanoVIP® |
Related products
-
Anti-Tumor-Associated Glycoprotein (TAG-90 BCA)
Price range: $250.00 through $1,079.00 Select options This product has multiple variants. The options may be chosen on the product page -
Anti-Insulin
Price range: $350.00 through $1,219.00 Select options This product has multiple variants. The options may be chosen on the product page -
Anti-Vimentin
Price range: $260.00 through $1,125.00 Select options This product has multiple variants. The options may be chosen on the product page -
Anti-Cytokeratin, Low MW
Price range: $260.00 through $1,119.00 Select options This product has multiple variants. The options may be chosen on the product page
