SATB2 (Special AT-rich binding protein 2) is a nuclear matrix protein that functions as a nuclear matrix-associated transcription factor. It binds to nuclear matrix attachment regions (MARS); displays functional versatility in central nervous development, especially corpus callosum and pons formation, skeletal development, osteoblast differentiation, cancer development and prognosis, as well as in immune regulation. SATB2 is highly expressed in adult brain, colorectal adenocarcinomas, moderately expressed in fetal brain, and weakly expressed in adult liver, kidney, and spinal cord.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: rSATB2/692
Source: Mouse
Tissue Type/Cancer Type: Hodgkins Lymphoma tissue

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