Anti- Retinoblastoma, Clone 13A10
Retinoblastoma gene / protein. Tumor suppressor gene at 13q14 it Encodes a 110-114 kDa nuclear protein that plays an important role in cell cycle progression by regulating cell cycle arrest at G1-S. Retinoblastoma (Rb) is a rare tumor of retina with mutations at chromosome 13Activation of ATF-2 initiate’s expression of TGF-beta2 which in turn inhibits transcription of genes affecting cell growth. Bilateral mutation of the Rb gene may play a role in the development of malignant tumors.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | 13A10 |
| Source | Mouse |
| Tissue Type/Cancer Type | Tonsil tissue |
| Pack | 6 mL (RTU), 100 Tests – Automation – i6000, 1 mL(Conc.), 0.5 mL (Conc.), 160 tests – Xmatrx Elite, 50 tests – Xmatrx Elite, 5 slides – Xmatrx, 5 slides – Manual |
