Anti-Prostein, Clone A-5


Prostein (Prostate cancer-associated protein 6) is a prostatespecific, 553 amino acid type IIIa plasma transmembrane protein that is upregulated by androgens. It has a perinuclearlike staining pattern, as expression is found in the Golgi complex of prostate cells. Prostein was positive in 99% of metastatic prostate adenocarcinomas while 97% of cases were positive for PSA. Prostein in conjunction with PSA improves identification of prostatic origin in unknown primary lesions, when staining alone with Prostein or PSA. Prostein is useful in diagnosing and monitoring prostate cancer.
Intended Use: IVD