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Anti-Progesterone Receptor (PR)

SKU: AN711GP Categories: , , ,
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Product Description

The human progesterone receptor (PR), is a ligand-activated transcription factor and is a member of the steroid receptor family. PR exists in human as two isoforms; PR-A (94 kDa) which lacks the first 164 amino acids of PR-B and PR-B(114 kDa). While the two forms of PR have similar DNA and Ligand binding affinities they have opposite transcriptional activities PR-B functions as an activator of progesterone-responsive genes, while PR-A functions as a strong transdominant repressor of PR-B. This anti-PR recognizes both PR-A and B. It labels epithelial cells of breast, ovary and endometrium.

Intended Use

ASR

Antibody Type

Monoclonal

Clone

EP2

Source

Rabbit

Tissue Type/Cancer Type

Breast Ca

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual