Human placental alkaline phosphatase (PLAP) of molecular mass 60-70kDa, is a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters and it is a oncofetal antigen. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes . PLAP and/or PLAP-like isoenzymes have been identified to be expressed by malignant tumors of germ cell and non-germ cell origin . The antibody reacts with PLAP in syncytiotrophoblasts in placenta and also reacts with human germ cell tumors.
|Tissue Type/Cancer Type|
0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual