PAX2 (paired box 2) proteins are tissue specific transcription factors that belong to “PAX family” which are active during early embryogenesis. It plays a critical role in the development of the nervous and excretory systems including the optic stalk, ear, midbrain-hindbrain junction, spinal cord, kidney, and urogenital tract. The expression of PAX2 is observed in condensing metanephric mesenchyme and in early epithelial structures in developing kidney but disappears as the tubular epithelium matures. Persistent expression of Pax-2 is seen in the undifferentiated epithelium of Wilms’ tumors.
|Tissue Type/Cancer Type||
Ovarian cell carcinoma tissues
1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual