P504S is a prostate cancer-specific gene and it encodes a protein Alpha-Methylacyl-Coenzyme A Racemase that is involved in beta-oxidation of branched-chain fatty acid and bile acid intermediates. P504S antibody binds to the human Alpha Methylacyl CoA Racemase present in the cytoplasm of target prostatic cells. Immunohistochemical Analysis showed high expression of AMACR (P504S) protein in prostatic adenocarcinoma but not in benign prostatic tissue. Several studies reported that AMACR can be used as a prostate cancer biomarker along with staining p63 as a negative marker. P504S gene expressed cytoplasmic protein is used for screening of prostate carcinoma
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | RBT-AMACR |
| Source | Rabbit |
| Tissue Type/Cancer Type | Prostate Ca |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
