DatasheetSDS

Osteonectin is a 32,000 dalton bone-specific protein that binds selectively to both hydroxyapatite and collagen. Osteonectin is present in active osteoblasts and young osteocytes of bone tissue, it is concerned with the mineralization of skeletal tissue. Osteonectin is a widely accepted Osteo-specific differentiation marker of normal osteogenic cells. Osteonectin accounts for 10% of the total protein content of bone. Osteonectin is one of the non-collagenous components and is bone-specific due to its biochemical properties. Osteonectin is a useful biochemical marker for bone-related tumors. Osteonectin antibody is can be used to demonstrate the presence of osteonectin in active osteoblasts and osteoprogenitor cells as well as in young osteocytes