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Anti-Oct-2

SKU: AN830GP Categories: , ,
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Product Description

Octamer transcription factor-2 (OCT-2) leucine zipper possessing transcription factor and it belongs to the POU family of transcription factors. OCT-2 is expressed in mature B cells, predominantly germinal center B cells. OCT-2 regulates key elements of gene expression during B cell development. ?OCT-2 transcription factor binds to the octamer motif (5- ATTTCAT-3), induces expression of immunoglobulin genes. OCT- 2 gene expressions in neuronal cells and epithelial cells have also been reported. The OCT-2 antibody labels various B cell lymphomas with strong expression in germinal center-derived lymphomas. Recent study on Hodgkin’s lymphoma (HL) reported that, OCT-2 positivity has been identified in 15 out of 15 lymphocyte predominance HLs, but none expression has been seen in the 29 classic HLs.

Intended Use

IVD

Antibody Type

Monoclonal

Clone

EP115

Source

Rabbit

Tissue Type/Cancer Type

Tonsil

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual