NKX2.2 is a member of NKX family of transcription factors. It is a homeodomain-containing transcription factor which is necessary for neuroendocrine differentiation in the central nervous system and pancreas. It is also involved with neuronal developing, patterning, and fate specification of neurons and oligodendrocytes. NKX2.2 expression has been found in the developing forebrain, spinal cord, Ewing’s sarcoma and neuroendocrine tumors of the gut. NKX2.2 antibody is considered as a sensitive panel marker for distinguishing Ewing’s sarcoma from other round blue cell tumors.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | D-4 |
| Source | Mouse |
| Tissue Type | Prostate Carcinoma Tissue |
| Pack | 6 mL (RTU), 10 mL (RTU), 1 mL(Conc.), 0.5 mL (Conc.), 50 tests – Xmatrx Elite, 160 tests – Xmatrx Elite, 5 slides – Manual, 5 slides – Xmatrx |
