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Anti-NGF-Receptor (p57)/ CD271

SKU: AMB85-5M_GP Categories: , , ,
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Product Description

NGFR (Nerve Growth Factor Receptor), also termed p75 or CD271, is the low-affinity NGFR (LNGFR) which binds NGF and other neutrophils, including BDNF, NT3 and NT4/5 with similar low-affinity. It is expressed in neuronal cells in various tissues and tumors with neuronal origin. Recent studies suggested that NGFR is also expressed in melanocytes, myoepithelial cells, basal-like cells, perivascular cells and lymphoid dendritic cells. NGFR is expressed not only in sympathetic and sensory neurons, but also in various neural crest cells or tumor derivatives such as melanocytes, Melanomas, Neurobastomas, Pheochromocytomas, Neurofibromas and neurotizednevi(Type C Melanocytes).

Intended Use

IVD

Clone

NGFR5+NTR/912

Pack

6 mL (RTU), 10 mL (RTU), 1 mL(Conc.), 0.5 mL (Conc.), 200 tests – Xmatrx Elite, 50 tests – Xmatrx Elite, 5 slides – Xmatrx, 5 slides – Manual