Neurofilaments (10 nm diameter) and microtubules (25 nm diameter) constitute the main structural components of neuronal dendrites, neuronal axons and perikerya. Three major polypeptides with approximate molecular weights of 200 kD, 160 kD and 68 kD combine to form a triplet referred to as the neurofilament. This antibody can be used for positive identification of neurons in the central and peripheral nervous systems. In general, co-expression of keratin and neurofilament should be interpreted as indicating neuroendocrine differentiation of a given tissue or neoplasm
Intended Use | IVD |
---|---|
Antibody Type | Monoclonal |
Clone | NE-14 |
Source | Mouse |
Tissue Type/Cancer Type | Nerve |
Pack | 6 mL – Manual – RTU, 100 Tests – Automation – i6000, 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP®, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |