Anti-NESTIN, Clone NES/2911


It is required for brain and eye development. It also promotes the disassembly of phosphorylated vimentin intermediate filaments(IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Nestin is required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells. Nestin is a marker for neuroepithelial stem cells, glioma cells and tumor endothelial cells during rapid growth. Nestin is also expressed by dermatomal cells and by myoblasts during the earliest stages of myogenesis.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: NES/2911
Source: Mouse
Tissue Type/Cancer Type: Kidney tissue