Myogenic factor are muscle specific basic-helix-loop-helix (HLH) structure transcription factors consisting of an amino acid-rich region belongs to the family of the muscle regulatory proteins, myogenic factors promote development of muscle and by transactivation of muscle specific genes. Myogenin, is a key transcription regulatory factors, that is crucial for differentiation and commitment of ?embryonic mesenchymal cells into skeletal muscle. Myogenin expression of is specific to embryonic skeletal muscle cells, but undetected in adult skeletal muscles. Myogenin is considered as extremely ?specific marker for diagnosing rhabdomyosarcomas
Intended Use: IVD
Antibody Type: Monoclonal
Clone: EP162
Source: Rabbit
Tissue Type/Cancer Type: Rhabdomyosarcoma