Myeloperoxidase (MPO) is a heme protein essential for innate immunity and is primarily located in neutrophils. It plays a critical role in pathogen defense by producing antimicrobial hypochlorous acid from hydrogen peroxide. While it is crucial for immune responses, MPO-generated reactive oxidant species, including hypochlorous acid, can also contribute to tissue damage during inflammation. Clinically, MPO serves as a valuable marker for identifying neoplastic tissues, aiding in the detection of cells associated with various cancers like acute myelogenous leukemia and progranulocytic leukemia.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | MPO/7118 |
| Source | Mouse |
| Tissue Type/Cancer Type | Liver Carcinoma |
| Pack | 6 mL – Manual – RTU, 100 Tests – Automation – i6000, 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP®, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
