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Anti-Mum/IRF4

SKU: AN750GP Categories: , , ,
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Product Description

MUM1/IRF4 protein is a member of the interferon regulatory factor (IRF) family of transcriptional factors initially described as downstream regulators of interferon signaling. The quantity of this factor varies within the hematopoietic system in a lineage and stage-specific way. It is considered to be a key regulator of several steps in lymphoid, myeloid, and dendritic cell differentiation and maturation. MUM1/IRF4 expression is observed in many lymphoid and myeloid malignancies, and may be a promising target for the treatment of some of these neoplasms. MUM1 is a valuable marker for understanding and characterizing histogenesis of Bcell lymphomas. It is an excellent marker for Reed-Sternberg cells of classic Hodgkin’s disease.

Intended Use

IVD

Antibody Type

Monoclonal

Clone

SP114

Source

Rabbit

Tissue Type/Cancer Type

Hodgkins

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual