MUC4 is a membrane-associated protein of the mucin (MUC) gene family, encoded by a gene on chromosome 3q29 and produced by epithelial cells as a heterodimer. The MUC4 protein is thought to play a protective role for vulnerable epithelia, particularly in the airway, eye, female reproductive tract, and mammary gland. Alterations in MUC4 expression have been observed in association with a variety of inflammatory and neoplastic states; including non-small cell lung carcinoma, hyperplastic polyps of the colon, and serrated colon adenomas, and breast carcinoma.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | 1G8 |
| Source | Mouse |
| Tissue Type/Cancer Type | Colon Ca |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
