MUC4 is a membrane-associated protein of the mucin (MUC) gene family, encoded by a gene on chromosome 3q29 and produced by epithelial cells as a heterodimer. The MUC4 protein is thought to play a protective role for vulnerable epithelia, particularly in the airway, eye, female reproductive tract, and mammary gland. Alterations in MUC4 expression have been observed in association with a variety of inflammatory and neoplastic states; including non-small cell lung carcinoma, hyperplastic polyps of the colon, and serrated colon adenomas, and breast carcinoma.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: 1G8
Source: Mouse
Tissue Type/Cancer Type: Colon Ca

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