Anti-MTAP
MTAP (S-methyl-5′-thioadenosine phosphorylase) is an enzyme that plays a major role in polyamine metabolism and is essential for salvage pathway. It catalyzes the cleavage of methylthioadenosine (MTA) into salvageable intermediates including adenine and 5-methylthioribose-1-phosphate. The expression of MTAP is seen in all normal cells but it is deficient in various cancers such as primary leukemia, lung cancer, melanoma, bladder cancer, gliomas and breast cancer.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | MTAP/1813 |
| Source | Mouse |
| Tissue Type/Cancer Type | Kidney tissue |
| Pack | 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
