MTAP (S-methyl-5′-thioadenosine phosphorylase) is an enzyme that plays a major role in polyamine metabolism and is essential for salvage pathway. It catalyzes the cleavage of methylthioadenosine (MTA) into salvageable intermediates including adenine and 5-methylthioribose-1-phosphate. The expression of MTAP is seen in all normal cells but it is deficient in various cancers such as primary leukemia, lung cancer, melanoma, bladder cancer, gliomas and breast cancer.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: MTAP/1813
Source: Mouse
Tissue Type/Cancer Type: Kidney tissue