MMP-9 or 92-kDa Type IV Collagenase or gelatinase B is a peptidase enzyme ?of Matrix metalloproteinases (MMP?s) family, it ?has a significant role in extracellular matrix component degradation during regular physiological phenomenon, such as reproduction, embryonic development, tissue remodeling and disease processes. MMP-9 is secreted as a pro-enzyme of 92-kDa by macrophages, neutrophils, mast cells and stromal cells and activated in inflammaroty tissues then released into the extracellular environment. MMP-9 expression levels in a variety of cancer types, including breast, colon, gastric and nasopharyngeal cancers are elevated compared with the corresponding normal tissues
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | EP127 |
| Source | Rabbit |
| Tissue Type/Cancer Type | Bone Marrow |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
