The protein encoded by this gene is a highly conserved mini chromosome maintenance protein (MCM) which is essential for the initiation of eukaryotic genome replication. The hexametric protein complex formed by the MCM proteins is a key component of the pre-replication complex which is involved in the formation of replication forks and with the recruitment of other DNA replication related proteins. Meier-Gorlin Syndrome 1 and Follicular Adenoma are the diseases associated with MCM7. The related pathways are Mitotic G1-G1/S phases and CDK-mediated phosphorylation and removal of Cdc6.
Intended Use | IVD |
---|---|
Antibody Type | Monoclonal |
Clone | SPM379 |
Source | Mouse |
Tissue Type/Cancer Type | Tonsil Tissue |
Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |