The monoclonal antibody produced by clone AA1 reacts with human mast cell tryptase in different tissues. Relatively high levels of the enzyme are found in mast cells of skin and lung. Tryptase, a structurally unique trypsin like serine protease, is a biochemical marker that has proven useful for disorders that involve systemic mast cell activation. It is shown to be implicated as a potential mediator in the pathology of several mast cell related allergic and inflammatory conditions, including rhinitis, conjunctivitis, and most notably asthma
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | AA1 |
| Source | Mouse |
| Tissue Type/Cancer Type | Skin |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
