Mammaglobin is a 10kDa breast-associated glycoprotein distantly related to secretoglobin family that includes human uteroglobin and lipophilin. It labels cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung and thyroid tissue. Anti-Mammaglobin is a sensitive and fairly specific marker for breast carcinoma and is used in a panel with GCDFP-15 and estrogen receptor (ER) in evaluating tumors of unknown primary origin.
Breast Carcinoma Tissue
6 mL (RTU), 100 Tests – Automation – i6000, 1 mL(Conc.), 0.5 mL (Conc.), 50 tests – Xmatrx Elite, 160 tests – Xmatrx Elite, 5 slides – Manual, 5 slides – Xmatrx