Lysozyme is a 14.4 kDa enzyme that has bacteriolytic function which is critical for mammalian innate immune function. It destroys bacterial cell wall peptidoglycan by hydrolyzing the polysaccharide component of the cell wall. Lysozyme is present in cytoplasmic granules of polymorphonuclear neutrophils (PMN) and is released through mucosal secretions such as tears and saliva. Expression of Lysozyme is seen in granulocytes, myeloid cells, histiocytes, monocytes and macrophages in human tonsil, skin, spleen, lung, kidney and colon. Lysozyme is an important marker in detecting the myeloid or monocytic nature of Acute Leukemia, large lymphocytes and histiocytic neoplasias, as well as classifying lymphoproliferative disorders.
| Intended Use | IVD |
|---|---|
| Antibody Type | Cytoplasm & Extracellular |
| Clone | LYZ/3943 |
| Source | Mouse |
| Tissue Type/Cancer Type | Tonsil, Spleen, Lung, Kidney tissue as available with |
| Pack | 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 6 mL – Manual – RTU, 10 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 160 Tests – Automation – Xmatrx |
