LI-cadherin (also known as CDH17) belongs to calciumdependent, membrane-associated glycoproteins of the cadherin superfamily. Their function is to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The expression of LI-cadherin is restricted to Liver and intestine tissues and plays a role in the morphological organization of hepatocytes and enterocytes. It has been shown to be a useful marker for distinguishing between primary urinary bladder adenocarcinoma and urothelial carcinoma with glandular differentiation.
Intended Use | IVD |
---|---|
Antibody Type | Monoclonal |
Clone | CAEX3 |
Source | Mouse |
Tissue Type/Cancer Type | Colon tissue |
Pack | 6 mL (RTU), 100 Tests – Automation – i6000, 1 mL(Conc.), 0.5 mL (Conc.), 160 tests – Xmatrx Elite, 50 tests – Xmatrx Elite, 5 slides – Xmatrx, 5 slides – Manual |