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Anti-Lambda Light Chain [Polyclonal]

SKU: AR049GP Categories: , , ,
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Product Description

The basic structure of an immunoglobulin molecule consists of two identical chains either ?, ?, ?, ? or ? and two identical light chains, either kappa or lambda. The gene rearrangement of immunoglobulin light chain coding gene results in either a productive kappa or lambda gene. The ratio of lambda and kappa light chain varies between different subclasses of Ig. The lambda chain antibody labels the lambda light chain that expresses normal and neoplastic B lymphocytes and plasma cells. Other cells may also express lambda light chain due to nonspecific uptake of imunoglobulin. The occurrence of a mixture of kappa and lambda chain expressing cells suggests a polyclonal population and a reactive or non-reactive proliferation of B cells.

Intended Use

IVD

Antibody Type

Polyclonal

Clone

Polyclonal

Source

Rabbit

Tissue Type/Cancer Type

Tonsil

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual