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This antibody reacts specifically with kappa light chain of human immunoglobulin and not lambda light chain and is reactive with intact IgG (kappa), IgM (kappa), free kappa light chains, and Bence-Jones kappa light chains. Applications utilizing monoclonal antibodies to kappa and lambda light chains have focused on the evaluation of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas, the majority of which derive from B-cell lineage. The most important use of this antibody would be in distinguishing atypical reactive follicular lymphoid hyperplasia from
follicular lymphoma, undifferentiated carcinoma from large cell lymphoma, pseudolymphoma from lymphoma, and reactive plasmacytosis from well differentiated plasmacytoma.
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0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual