Insulin is synthesized in the beta cell of the pancreas. It is a glucose homeostasis regulating hormone. It acts by increasing cell permeability to monosaccharides, amino acids and fatty acids, and accelerating glycolysis, the pentose phosphate cycle, and glycogen synthesis in the liver. One million to three million islets of Langerhans (pancreatic islets) form the endocrine part of the pancreas, which is primarily an exocrine gland produces Insulin. The endocrine portion accounts for only 2% of the total mass of the pancreas. Within the islets of Langerhans, beta cells constitute 65-80% of all the cells. The antibody labels both normal and neoplastic insulin-producing cells. It is useful in identifying insulinoma
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | EP125 |
| Source | Rabbit |
| Tissue Type/Cancer Type | Pancreas |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
