Anti- IL-5


Interleukin-5 (IL-5), also called as T cell-replacing factor (TRF) is a T-cell derived cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. It is a critical regulator for eosinopoiesis, eosinophil maturation and activation. IL-5 binds to its receptor which is a heterodimer and regulates the expression of genes required for cell proliferation, survival and maturation. JAK-STAT, Btk and Ras/Raf-ERK signalling pathways regulates the cellular functions of IL5. IL-5 is considered as a target for the treatment of eosinophilic diseases.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: IL5/4161
Source: Mouse
Tissue Type/Cancer Type: Thymus, Tonsil, Adrenal gland, Stomach tissues