Interleukin 2 (IL-2) (also designated T Cell Growth Factor (TCGF) or Aldesleukin or Lymphokine 2) is a T cell stimulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, LAK cells, natural killer cells, monocytes, macrophages and oligodendrocytes. It also induces CTLA-4 and promotes peripheral development of regulatory T cells (Tregs). IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. Contrarily, it is involved in the activation-induced cell death (AICD) that is observed post T cell expansion by increasing levels of Fas on CD4+ T cells.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | IL2/3949 |
| Source | Mouse |
| Tissue Type/Cancer Type | Colon Tissue |
| Pack | 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
